Vol.2, No 5, 2003 pp. 293 - 299
UDC 577.118; 547.562.2
SALTING-OUT EXTRACTION OF CATECHOL
AND? HYDROQUINONE FROM AQUEOUS SOLUTIONS
AND URINE SAMPLES
Goran M. Nikolić1, Jelica M. Perović2,
Ružica S. Nikolić2, Milorad M. Cakić3
1Department of Chemistry, Faculty of
Medicine, University of Niš,
Braće Tasković 81, 18000 Niš, Serbia and Montenegro
2Department of Chemistry, Faculty of
Sciences, University of Niš,
Višegradska 33, 18000 Niš, Serbia and Montenegro
3Faculty of Technology, University
of Niš,
Bulevar oslobođenja 124, 16000 Leskovac, Serbia and Montenegro
Abstract. The influence of ammonium, sodium, potassium, and magnesium
chlorides and sulfates on the extraction of catechol and hydroquinone with
diethyl and diisopropyl ether was studied. All the salts investigated in
this study largely increased the extraction efficiency of both catechol
and hydroquinone from aqueous solutions, magnesium salts being the most
efficient salting-out agents. The extraction efficiency in the presence
of magnesium salts in comparison to the extraction efficiencies from the
salt-free aqueous solutions increased from 14%, in the case of catechol
extraction with diethyl ether, up to about 90%, in the case of hydroquinone
extraction with diisopropyl ether. The extraction from spiked urine samples
proved that investigation of salting-out effect in aqueous solutions could
be used as a good model system for the reliable choice of optimal conditions
for catechol and hydroquinone extraction from real samples.
Key words: salting-out, extraction, catechol, hydroquinone
UTICAJ ISOLJAVANJA NA EKSTRAKCIJU KATEHOLA
I HIDROHINONA IZ VODENIH RASTVORA I URINA
Ispitivan je uticaj amonijum, natrijum, kalijum i magnezijum hlorida i
sulfata na ekstrakciju katehola i hidrohinona dietil i diizopropil etrom.
Sve soli ispitivane u ovom radu su znatno povećale efikasnost ekstrakcije
i katehola i hidrohinona iz vodenih rastvora, pri čemu su najbolji efekat
isoljavanja pokazale magnezijumove soli. Efikasnost ekstrakcije u prisustvu
magnezijumovih soli u odnosu na efikasnost ekstrakcije iz vodenih rastvora
bez dodatka soli povećana je od 14% (kod ekstrakcije katehola dietil etrom)
do čak 90% (kod ekstrakcije hidrohinona diizopropil etrom). Ekstrakcija
uzoraka urina sa dodatkom fenolnih jedinjenja potvrdila je da se ispitivanje
efekta isoljavanja iz vodenih rastvora može koristiti kao dobar model sistem
za pouzdan izbor optimalnih uslova za ekstrakciju katehola i hidrohinona
iz realnih uzoraka.
