Vol.15, No 3, 2008 pp. 103 - 107
UC 616.9-036.22
PROTEAN NATURE OF INFECTIOUS DISEASES
– TRENDS IN THE TERRITORY OF THE REPUBLIC OF SERBIA
Miodrag Vrbić1, Biljana Vrbić2,
Svetislav Vrbić3, Maja Jovanović1
1Clinic for Infectious Diseases,Clinical
Centre Niš, Republic of Serbia
2Clinic for Pulmonary Diseases,Clinical
Centre Niš, Nis, Republic of Serbia
3Clinic of Oncology, Clinical Centre
Niš, Republic of Serbia
E-mail: mvrbic@eunet.rs
Summary. About 59 Lactobacillus isolates were isolated from 5 different
fresh water sites such as Cat fish (Clarias orientalis), Hari fish (Anguilla
sp), Rohu fish (Labeo rohita), Jillabe fish (Oreochromis sp) and
Gende fish (Punitus carnaticus). Among the 59 isolates only 4 Lactobacillus
isolates were selected for further study. Based on morphologiIn infectology,
more than anywhere else in medicine, we are witnessing the variability,
vicissitude of pathology. The changes of the relationship of man and his
microbial environment have been especially dynamic in the last decades.
In order to define the nature of this process, its possible origin and
regularity, we compared the reports on infectious diseases in the Republic
of Serbia for 1987 (from 1983 to 1987) and 2004 (from 2000 to 2004). A
statistically significant reduction of morbidity was found, caused by a
reduced incidence of vaccine-preventable infections (rubella, mumps morbilli,
pertussis) and infections related to basic hygiene habits and sanitation
(gastrointestinal tract infections, scabies, viral hepatitis type A, gonorrhoea...).
On the other hand, there were significantly more infections caused by infectious
mononucleosis and morbus Lyme agents, which have a specific relationship
with the immune system, as well as the diseases which are the consequence
of immune deficiency, such as herpes zoster or fungal diseases. At the
same time, paradoxically, changes in the immune status and increased microbial
resistance are the basis of a significant increase of mortality from infectious
diseases. Overall, the evolution of our relationship with microbial environment
is the consequence of general social progress, as well as the progress
of medicine itself, and this relationship is nowadays characterized by
the prevalence of infections caused by the microbial agents conditionally
compromising with their hosts.
Key words: Infectious disease,
epidemiology, protean, Republic of Serbia
PROTEJSKA PRIRODA INFEKTIVNIH BOLESTI
– KRETANJE ZARAZNIH BOLESTI NA TERITORIJI REPUBLIKE SRBIJE
Kratak sadržaj: U infektologiji, više nego bilo gde drugde u medicini,
svedoci smo promenljivosti, nestalnosti patologije. Ove izmene odnosa čoveka
i njegovog mikrobnog okruženja posebno su dinamične poslednjih par decenija.
U cilju definisanja prirode tog procesa, njegovog mogućeg porekla i zakonitosti,
upoređivani su izveštaji o kretanju zaraznih bolesti u Republici Srbiji,
za 1987. (od 1983. do 1987.) i 2004. (od 2001. do 2004.) godinu. Utvrđen
je statistički značajan pad morbiditeta, uslovljen smanjenom incidencijom
vakcinama preventabilnih infekcija (rubella, mumps, morbilli, pertussis)
i infekcija povezanih sa osnovnim higijenskim i zdravstvenim navikama (infekcije
gastointestinalnog trakta, scabies, hepatitis virosa A, gonorrhoea...).
Sa druge strane, verifikovana je značajno veća učestalost infekcija
uzročnicima infektivne mononukleoze i Lyme borelioze, koji su u specifičnom
odnosu sa imunskim sistemom, kao i oboljenja koja su rezultat imunodeficijencije,
poput herpes zostera ili gljivičnih oboljenja. Istovremeno, izmene imunskog
statusa i povećana mikrobna rezistencija su osnov, naizgled paradoksalnog,
značajnog povećanja mortaliteta infektivnih bolesti. Generalno gledano,
evolucija našeg odnosa sa mikrookruženjem posledica je ubrzanog opšteg
društvenog napretka, kao i napretka same medicine. Ovaj odnos je sada
neposredniji nego ikad i karektarisan je prevladavanjem infekcija mikrobnim
agensima koji su našli uslovni kompromis sa svojim domaćinom.
Ključne reči: infektivne
bolesti, epidemiologija, protejski, Republika Srbija
