Vol.15, No 1, 2008 pp. 7 - 12
UC 615.281
AN ANTIFUNGAL COMPOUND: 4' PHENYL -1-NAPTHYL
-PHENYL ACETAMIDE FROM STREPTOMYCES SP. DPTB16
Dharumaduari Dhanasekaran1, Nooruddin
Thajuddin1, Annamalai Panneerselvam2
1Department of Microbiology, School
of Life Sciences, Bharathidasan University, Tiruchirappalli, 620 024, India
2P.G. & Research Department of
Botany & Microbiology, A.V.V.M. Sri Pushpam College, (Autonomous),
Poondi, 613 503 Thanjavur District, Tamil Nadu, India
E-mail: dhansdd@yahoo.co.in
Summary. The identification of antifungal compound was made by determining
the melting point, by means of elemental analysis and spectral analysis
such as UV, IR, NMR and Mass spectra. Based on the spectral characteristics,
the antifungal compound was identified as 4' phenyl-1-napthyl-phenyl acetamide
from Streptomyces sp. DPTB16. It showed antifungal activity against Candida
albicans followed by Aspergillus niger, A. fumigatus, A. flavus and minimum
inhibitory activity was observed with Mucor sp. and Penicillium sp.
Key words: Marine Streptomyces,
Sea shore soil, Antifungal assay
ANTIGLJIVIČNO JEDINJENJE: 4' FENIL –
1 – NAFTALIN – FENIL ACETAMID IZ VRSTE STREPTOMYCES DPTB16
Kratak sadržaj: Identifikacija antigljivičnih jedinjenja izvršena
je odredjivanjem tačke topljenja, elementalnom analizom i spektralnom
analizom kao sto su UV, IR, NMR i spektri mase. Na osnovu spektralnih karakteristika,
antigljivično jedinjenje je identifikovano kao 4' fenil – 1 – naftalin
– fenil acetamid iz vrste Streptomyces DPTB16. Pokazalo je antigljivičnu
aktivnost na Candidu albicans koju su pratile Aspergillus niger, A. fumigatus,
A. flavus a minimalna inhibitorna aktivnost je primećena sa Mucor sp.
i Penicillium sp.
Ključne reči: morske Streptomyces,
obalna zemlja, antigljivični test
