Vol.14, No 3, 2007 pp. 133 - 137
UC 616.594-002:616.5-006

CARCINOMA ARISING IN PILONIDAL DISEASE – REPORT OF TWO CASES
Predrag Kovacevic1, Milan Visnjic1, Milica Vukadinovic2, Tatjana Kovacevic3, Dragan Mihajlovic4
1Clinical Center Nis, Clinic for Plastic and Reconstructive Surgery
2Medical Faculty Nis
3Clinical Center Nis, Clinic for Anesthesia and Reanimation
4Clinical Center Nis, Clinic for General Surgery
E-mail: tpkovacevic@eunet.yu

Summary. Squamous cell skin carcinoma is a rare complication of pilonidal disease. The signs of malignant change are induration, rapid growth and sharp pain in ulcerated tumor. Men are mostly involved. Histology defined highly differentiated squamous carcinoma in one and a bad differentiation in the other. Carcinoma in pilonidal disease mainly arises after 15 year disease history. Two men were operated on for this carcinoma at Surgical clinic of Nis. After biopsy, carcinoma was operated radically (large excision) and margins needed to be clean. Immediate reconstruction was performed with skin grafts and musculocutaneous gluteus maximus peddicled flap. Postoperative radiation therapy was performed. One patient is disease free after 3 years, but other died 9 months after surgery. The primary prevention from carcinoma is surgery for early pilonidal disease. Large surgical ressection and clean margins could obtain satisfactory results.
Key words: Pilonydal disease, skin carcinoma, surgery

KARCINOM NASTAO IZ PILONIDALNOG SINUSA – PRIKAZ DVA SLUČAJA
Kratak sadržaj: Karcinom na pilonidalnom sinusu je retka komplikacija bolesti. Sumnju hirurga treba da pobudi induracija i rast ulcerisanog tumora kao i pojava jakih bolova. Češće se javlja kod muškaraca. Patohistološki je dobro diferentovan planocelularni karcinom kod jednog, a kod drugog loše diferentovan. Ovaj tumor nastaje kod pacijenata sa dugogodišnjom anamnezom (preko 15 godina). Dva pacijenta sa pilonidalnim karcinomom su operisana u Hirurškoj klinici u Nišu. Hirurško lečenje pacijenta sa karcinomom na pilonidalnom sinusu zaheva široku radikalnu hiruršku eksciziju uz kontrolu resekcionih ivica i primarnu rekonstrukciju defekta.Rekonstrukcija defekta je rađena transplantatima kože i režnjevima. Postoperativno je sprovedena zračna terapija. Jedan bolesnik posle 3 godine nema znakove za recidiv niti metastaze, a drugi bolesnik je umro nakon 9 meseci od operacije. Najbolja prevencija karcinoma nastalog iz pilonidalnog sinusa je hirurško lečenje pilonidalne bolesti u ranoj fazi. Radikalna hirurška ekscizija sa kontrolom ivica resekcije može obezbediti uspeh u lečenju.
Ključne reči: pilonidalna bolest, karcinom kože, hirurgija