Vol.14, No 2, 2007 pp. 101 - 105
UC 615.26:616.53-002

EFFECTS OF RENDERED SUPERFICIAL AHA´S PEELINGS WITH PATIENTS WITH ACNE COMEDONICA ET PAPULOSA
Sanja Perić1, Maja Bubanj2, Saša Bubanj3
1Centar estetske medicine-Dom zdravlja u Nišu,
2Medicinski fakultet u Nišu,
3Fakultet sporta i fizičkog vaspitanja u Nišu

Summary. Acne vulgaris is an ailment of pilosebaceous follicle which is multifarious by nature. It represents the most frequent chronic sickness with teenagers. The apparation of acnes can be shortly characterized on several levels: reinforced secretion of sebum, bacterial proliferation, local inflammation and hyperceratosis. According to some research, about 80% of young people between 12 and 24 years encounter that sickness. Regarding the diversity of possible causes which lead to the pathogenesis of acne, there are several approaches in treatment of this ailment. Beside the classical treatments, due to considerable results, there has recently been given big attention to treating acne by using preparations based on alfa hydroxill acids (AHA). In addition, there is a big importance of adequate care during the therapy in terms of hydration and anti-inflammatory and epithelisant substance.
The aims of this research were to establish the efficiency of peelings with AHA, to evaluate various concentrations of acids (20%, 40%, 70%), to establish adequate therapeutic concentrations, to test undesirable effects of this therapy and establish the importance of care on everyday basis. The examination was effected in the Centre for Esthetic Medicine-The Health Centre in Niš.
The selection of 60 examinees was divided into 4 sub-groups (patients with acne comedonica et papulosa). Testing areas were 5x5 cm, left and right cheek paralelly.
The therapy was effected once a week and lasted 8 weeks, when analysis, clinical examination and marks inserting in the protocol of research were made. All examinees went through the complete treatment.
The best therapeutical effects with minimum undiserable apparition were obtained by using AHA acids 40%.
Key words: Alpha hydroxil acids, acne comedonica et papulosa, superficial chemical peeling

EFEKTI PONOVLJENIH SUPERFICIJALNIH PEELINGA ALFA HIDROKSI KISELINAMA
KOD PACIJENATA SA OBOLJENJEM AKNE TIP I
Kratak sadržaj: Acne vulgaris je oboljenje pilosebacealnog folikula multifaktorijalne prirode. Predstavljaju najčešće hronično oboljenje adolescentne dobi. Nastanak akni vezuje se za kožne pore, odnosno folikul? dlaka i pripadajuće lojne zlezde. Predilekciono mesto za nastanak akni jesu seboroične regije, a primarna promena koja se javlja jeste mitiser ili komedon Prema nekim istraživanjima oko 80 % mladih između 12 i 24 godina susreće se sa tim oboljenjem. Obzirom na raznolikost mogućih uzroka koji dovode do nastanka akni i u lečenju postoji više pristupa. Osim klasičnih, u novije vreme zbog značajnih rezultata, sve veću pažnju privlači tretman akni preparatima na bazi AHA kiselina. Takođe se ističe veliki značaj adekvatne nege u toku terapije u smislu hidratacije i antizapaljenjskog i epitelizantnog sredstva.
Ciljevi ovog istraživanja su da se utvrdi efikasnost peelinga AHA kiselinama, vrednuju različite koncentracije kiselina (20%, 40%, 70%), utvrde adekvatne terapijske koncentracije, ispitaju neželjeni efekti ove terapije i utvrdi značaj svakodnevne nege.
Uzorak od 60 ispitanika podeljen je u četiri podgrupe (pacijenti sa acne comedonica et papulosa). Ispitivanje je izvršeno u Centru estetske medicine Dom zdravlja Niš.
Kao mesta testiranja procenjivana su polja 5x5cm, desni i levi obraz paralelno.
Terapija je trajala 8 nedelja, jednom nedeljno kada su vršene analiza, klinički pregled i unos ocena u protokol istraživanja. Svi ispitanici su završili kompletan tretman.
Najbolji, najbrži efekti poboljšanja postignuti su upotrebom 40 %-tne AHA kiseline.
Ključne reči: alfa hidroksi kiseline,  acne tip comedonica et papulosa, superficijalni hemijski peeling