Vol.14, No 1, 2007 pp. 6 - 9
UC
616.379:616.31
DIABETES AND PERIODONTAL DISEASE: A BIDIRECTIONAL RELATIONSHIP
Rosa María Díaz-Romero, Rubén Ovadía
Subdirection of Public Health Research at the National Institute of Perinatology (Instituto Nacional de Perinatología)
Mexico City, Mexico
E-mail: dra_diazromero@yahoo.com.mx
Summary.
Periodontal disease (PD) and diabetes mellitus (DM) hold a consistent relationship. DM not only increases the risk of having PD and with that its prevalence, but it also augments the progression of more aggressive and quickly defining signs. There is a bidirectional relationship between DM and PD. The treatment of periodontitis in diabetic patients favors a reduction in mediators responsible for the destruction of periodontal tissue and decreases with it, a resistance to insulin. PD is characterized by low grade chronic inflammation that may remain silent in diabetics causing damage that is not locally limited but may extend systemically.
Key words:
Periodontal disease, loss of glycemic control, low grade chronic inflammation
DIJABETES I PERIODONTALNA BOLEST: UZAJAMNI ODNOS
Kratak sadržaj:
Periodontalna bolest (PB) i diabetes mellitus (DM) su u doslednoj vezi. DM ne samo da povećava rizik od pojave PB, a samim tim i njegovu učestalost, nego i povećava progresiju znakova koji su agresivniji i koji se brže određuju. Postoji dvosmerna veza između DM i PB. Tretiranjem periodontitisa kod pacijenata sa dijabetesom, smanjuju se posrednici odgovorni za razaranje periodontalnog tkiva a samim tim smanjuje se i rezistentnost na insulin. PB karakteriše hronična upala niskog inteziteta koja može ostati prikrivena kod dijabetičara, uzrokujući štetu koja nije lokalno ograničena već može sistematično da se širi.
Ključne reči:
Periodontalna bolest, gubitak glikemičke kontrole, upala niskog inteziteta
