Vol.12, No 2, 2005 pp. 85 - 88
UC 616.12-008.315-053.2
SUDDEN CARDIAC DEATH IN CHILDREN
Lidija Kostić-Banović1, Radovan
Karadžić1, Jovan Stojanović1,
Goran Ilić1, Tatjana Stanković2
1The Institute for Forensic Medicine,
Faculty of Medicine Niš, Serbia and Montenegro
2Paediatric Clinic, Clinical Center
Niš, Serbia and Montenegro
Summary. Sudden cardiac death is defined as unexpected death
from
cardiac causes early after or without the onset of symptoms. Having in
mind that acute myocarditis may be a rare cause of sudden cardiac death
in children, we have undertaken the following study: clinical,
macroscopical
and histopathological characteristics of the myocardium of two
autopsied
children who died suddenly. A number of myocardial tissue specimens
were
fixed in formalin and embedded in paraffin. Laboratory sections were
stained
with HE, Van Gieson and PAS methods. The pathohistological features of
viral and acute rheumatic myocarditis were found. Coronary arteries and
valves were normal. Viruses are difficult to culture from myocardial
tissue,
but lymphocytic and monocytic infiltrates are histological markers of
viral
etiology and acute Aschoff bodies of rheumatic fever.
Key words: Viral myocarditis, rheumatoid myocarditis, children,
morphology
IZNENADNA SRČANA SMRT KOD DECE
Kratak sadržaj: Iznenadna srčana smrt se definiše kao
neočekivana
smrt srčanog porekla koja nastaje neposredno nakon ispoljene
simptomatologije,
ili bez pojave bilo kakvih simptoma. Imajući u vidu da akutni
miokarditis
može biti redak uzrok iznenadne srčane smrti kod dece, pratili smo
kliničke,
makroskopske i histopatološke promene miokarda kod dva autopsijska
slučaja
iznenada preminule dece. Fiksirani su brojni isečci srčano-mišićnog
tkiva
u formalinu i kalupljeni u parafin. Laboratorijski isečci su obojeni
HE,
Van Gieson i PAS metodom. Nadjene su patohistološke karakteristike
akutnog
virusnog i reumatoidnog miokarditisa. Nalaz na koronarnim arterijama i
valvulama je bio normalan. Viruse je teško izolovati iz srčano-mišićnog
tkiva, ali limfocitni i monocitni infiltrati su histološki markeri
miokarditisa
virusne etiologije, dok su Aschoff-ova tela markeri reumatske groznice.
Ključne reči: virusni miokarditis, reumatoidni miokarditis,
deca, morfologija
