Vol. 9, No 1, 2002 pp. 74 - 75
UC 616.61-004
VIRUS ISOLATION FROM THE KIDNEY, TUMORS
AND LYMPH NODES
OF PATIENTS WITH BEN
B. Uzelac-Keserović1, K. Apostolov2
1Institute of Immunobiology and Virology,
Torlak, Belgrade, Serbia
2Biology Section, Macedonian Academy
of Arts and Science (MANU), Skopje, Macedonia
Introduction
This paper is based on two recent publications (1,2), and one submitted
for publication (submittted for publi-cation). There is an important correction.
In the two previous publications in Nephron it was stated that the virus
isolated from the kidneys, the tumors and meta-static lymph glands
was classified as a coronavirus (1,2). Subsequent more detailed investigations
revealed that the virus should not be identified as a coronavirus (submittted
for publication). However, the evidence presented in this work suggests
strongly that the newly isolated virus is involved in the ethyology of
BEN. The new findings open the possibility of reassessment of this still
mysterious disease.
Conclusions
A virus was isolated from kidneys, tumors and meta-static lymph glands
from cases of BEN. The material was obtained at operations of tumors
of the urinary tract. The identity of the virus has yet to be established.
In cases of BEN with tumors, anti-bodies were found in all the patients.
The identity of the virus is the sub-ject of a companion paper (Riquelme
C, Escors D, Ortego J, Sanchez CM, Uzelac-Keserovic B, Enjuanes L. sub-mitted
for publication). The evidence presented sug-gests strongly that as yet
an unidentified virus is in-volved in the aetiology of BEN. There
are still many unresolved questions concerning the putative virus.
